Most of my shots end up at f/1.8 because of low light situations. I have gotten to the point I almost solely do center focus/compose. It's not always perfect, and I'm generally focused on moving targets so it's hard anyway. This is an example from last night - focused on his hand, then composed the shot. His hand is definitely well-focused in the larger sizes - and I have about 2" which are in focus at that range/aperture.