In CS3
lightly sharpened;
topaz filter to add definition in highlights lowlights in image;
used mask to soften the topaz effects;
duplicated layer, used healing brush and spot brush around eyes and nose, mask to bring mack some natural textures;
burned and dodged eyes, and teeth - added light color to even out teeth;
softened overall image (for skin) masked back sharpness in details - clothes, eyes, mouth, hair;
unsharp mask to fix contrasting and line details
viola!