I am a big fan of prime! (Optimus too, but that's another story) Seriously, I assume Nikon and Canon are similiar in that some lenses have USM tech (or whatever Nikon calls it) enabling really fast focusing, and sharpness. If that's the case, a lot of primes have it, while the zooms that do are EXPENSIVE! And if you're photographing people, you can almost always take one step forward or back.
If you want face shots, the 85mm f/1.8 or 100mm f/2 would be better than a 50mm in that you want to be far enough away for the average person not to be self-conscious
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