For this shot, I used a key-ring laser pointer reflected off the bottom of a stainless-steel teaspoon (to spread the laser beam out) to illuminate a blue gel-cap pill. Shot on May 25, 2009. No post production, other than to convert to jpg and resize the image.
Canon EOS Digital Rebel XTi
Shutter speed: .5 sec
f/5.6
ISO: 400
Focal Length: 55 mm
Lens: EF-S 18-55mm f/3.5-5.6 USM
Here's my ghetto setup (red 'beam' diagram added, of course

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